Relationship Between CD4 Count and Viral Load -- nickchinlund.info
Relation between CD4 count, Viral Load and Time of Infection (Nov 18, ). CD4, Viral load Questions about CD4 and viral load after HIV infection (Jul 15, ). Bringing my CD4 Need Good advice (Oct 8, ). CD4 Percentage. Sep 15, The direct relationship between quality of life and CD4 count is unclear. Africa assessed the change in CD4 count and viral load among HIV Rapid advice: antiretroviral therapy for HIV infection in adults and adolescents. CD4 COUNT This measure is an indication of the strength of the immune system. CD4 cells are an extremely important part of our immune system, HIV attacks.
The direct relationship between quality of life and CD4 count is unclear. The purpose of this study is to determine the relationship between change in CD4 count and quality of life measures in a Ugandan cohort of people living with HIV.
Generalized estimating equations were used to analyze the data.
The primary predictor variable was change in CD4 count, and the outcome was quality of life scores. We controlled for sociodemographic characteristics, clinical factors and behavioral factors.
- CD4 and viral load
- 2.14 How CD4 and viral load are related
Twenty in-depth interviews were conducted to assess patient perception of quality of life and factors influencing quality of life. There was no association found between change in CD4 count and quality of life scores at univariate and multivariate analysis among the study participants whether on or not on antiretroviral therapy. Participants perceived quality of life as happiness and well-being, influenced by economic status, psychosocial factors, and health status.
Conclusions Clinicians and policy makers cannot rely on change in immunological markers to predict quality of life in this era of initiating antiretroviral therapy among relatively healthy patients. In addition to monitoring immunological markers, socioeconomic and psychosocial factors should be underscored in management of HIV patients.
Background There is an established relationship between immunological and virological outcomes as important markers of HIV disease progression and treatment failure [ 12 ]. CD4 cell count has been reported to have a strong association with progression to AIDS-related illness or death [ 3 ]. Quality of life QoL has become an important outcome variable to be monitored, in addition to other clinical outcomes and biological markers such as CD4 count [ 4 ].
With the prolonged survival of HIV patients in resource-limited settings, the focus in HIV care is no longer only on clinical outcomes such as morbidity and mortality but on QoL as well. QoL measurement is now more essential than ever, to optimize patient outcomes [ 4 ]. If you are taking HIV treatment and have had an undetectable viral load, and then you have a test that shows a detectable viral load, you will need to have another test to confirm the result.
If later tests still show your viral load has become detectable again, you will probably need to change your HIV treatment. Your doctor will discuss your options with you. Their viral load increases from undetectable to a low but detectable level before becoming undetectable again on the next test. Viral load blips do not necessarily show that your HIV treatment is no longer working. There are a number of theories about the reasons for blips. These include variations in the laboratory processes, or having an infection like a cold or the flu.
How CD4 and viral load are related | Training manual | HIV i-Base
If your viral load stays above detectable on two consecutive tests, or possibly if you have fairly frequent blips, your doctor will want to discuss possible causes and whether you need to change your treatment. Viral load and sexual transmission of HIV If you have a high viral load in your blood, then you might also have a high viral load in other body fluids, including your semen or vaginal fluid. In the first few weeks after contracting HIV, viral load is usually extremely high.
People with high viral loads are more infectious and can pass HIV on more easily. On the other hand, if HIV in your blood is undetectable, it is likely to be undetectable in your semen, vagina fluid or rectum as well.
Having an undetectable viral load means that the risk of HIV being passed on is extremely low. The study is collecting more data and will have final results in A lot of people with HIV see the reduction of infectiousness and relief from anxiety about transmission as very important benefits of HIV treatment. You may wish to take your viral load and your likely infectiousness into consideration when thinking about safer sex. If you want to stop using condoms, it is important to wait six months after your first undetectable viral load test, to be sure that treatment is working.
It is also important to discuss this issue carefully with your partners and ensure they are also comfortable with the decision.
CD4 vs. Viral Load: What’s in a Number?
While HIV treatment and an undetectable viral load will protect your partners from your HIV, they do not protect them or you from other sexually transmitted infections STIs. Also, in some countries, condomless sex without disclosing your HIV status is a criminal offence, regardless of the likelihood of HIV transmission.
If you are using HIV treatment in order to prevent sexual transmission, it is recommended to have it checked more often every three to four months than might otherwise be the case. This is to check that your viral load is still undetectable. Drug resistance Another reason for regular viral load tests is to monitor any drug resistance to the prescribed HIV therapy. Maintaining a low viral load reduces the risk of developing resistance to the therapy.
Why is HIV therapy so important? It consists of a combination of antiretroviral drugs. This is called an undetectable viral load.
HIV & AIDS Information :: CD4, viral load & other tests - Viral load
If a person is virally suppressed or has an undetectable viral load, their HIV is under control. Current treatment guidelines from the U. Department of Health and Human Services recommend that a person living with HIV begin antiretroviral drugs as soon as possible after diagnosis. This is essential to reducing opportunistic infections and preventing complications from HIV. Another benefit to getting HIV under control and having an undetectable viral load is that it helps prevent the transmission of HIV to others.
No matter the stage of HIV, there are advantages to keeping track of these numbers. HIV treatment has come a long way in recent years. Following a recommended treatment plan and leading a healthy lifestyle can help a person keep their CD4 count high and their viral load low. Early treatment and effective monitoring can help a person manage their condition, reduce their risk of complications, and live a long and healthy life.